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|Pronunciation||/ ˈ aɪ b juː p r oʊ f ɛ n /, / aɪ b juː ˈ p r oʊ f ən /, EYE -bew- PROH -fən|
|Trade names||Advil, Motrin, Nurofen, others|
|License data||EU EMA: by INN, US FDA: Ibuprofen|
|Pregnancy category||AU: C US: C (Risk not ruled out) D (US) at ≥30 weeks of gestation, due to the potential for premature closure of the ductus arteriosus|
|Routes of administration||by mouth, rectal, topical, and intravenous|
|ATC code||C01EB16 ( WHO ) G02CC01 ( WHO ) M01AE01 ( WHO ) M02AA13 ( WHO ) R02AX02 ( WHO )|
|Legal status||AU: OTC CA : OTC UK: General sales list (GSL, OTC) US: OTC (R x -only at higher doses)|
|Bioavailability||80–100% (by mouth),  87% (rectal)|
|Protein binding||98% |
|Metabolism||Liver (CYP2C9) |
|Metabolites||ibuprofen glucuronide, 2-hydroxyibuprofen, 3-hydroxyibuprofen, carboxy-ibuprofen, 1-hydroxyibuprofen|
|Onset of action||30 min |
|Elimination half-life||2–4 h |
|Excretion||Urine (95%)  |
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Kiekvienoje 2 ml ampul je yra 1000 mg metamizolo natrio druskos monohidrato.with molar mass of 311. 6 g/mol.
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Suleidus ven, LD50 pel ms analgin tablete, 89 mg/kg k no svorio, o triu iams 1300 mg/kg k no svorio. Vidutin skausmo mal inamoji doz pel ms yra kelis kartus ma esn u vidutin mirtin.Metabolites also pass into breast milk.
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Om international database is in BETA release.In exceedingly sharp pains: the dose may be increased to 5ml of 50% solution administered intravenously.
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27. Vanegas, H, and V. Tortorici.0-22.
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Enhances the effect of ethanol; simultaneous use with chlorpromazine or other phenothiazine derivatives can lead to the development of severe hyperthermia fever X-ray contrast agents, colloidal blood substitutes, and penicillin should not be used during treatment with metamizole. With the simultaneous administration of cyclosporine, the concentration of the latter in analgin tableta blood decreases.These are very important problems allergy and antibiotic resistance can potentially take analgin tableta more lives than a.
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